Package: HIMA 2.3.1

HIMA: High-Dimensional Mediation Analysis

Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, Zhang W, Schwartz J, Just A, Colicino E, Vokonas P, Zhao L, Lv J, Baccarelli A, Hou L, Liu L. Estimating and Testing High-dimensional Mediation Effects in Epigenetic Studies. Bioinformatics. (2016) <doi:10.1093/bioinformatics/btw351>. PMID: 27357171.

Authors:Yinan Zheng [aut, cre], Haixiang Zhang [aut], Lifang Hou [aut], Lei Liu [aut, cph]

HIMA_2.3.1.tar.gz
HIMA_2.3.1.zip(r-4.5)HIMA_2.3.1.zip(r-4.4)HIMA_2.3.1.zip(r-4.3)
HIMA_2.3.1.tgz(r-4.5-any)HIMA_2.3.1.tgz(r-4.4-any)HIMA_2.3.1.tgz(r-4.3-any)
HIMA_2.3.1.tar.gz(r-4.5-noble)HIMA_2.3.1.tar.gz(r-4.4-noble)
HIMA_2.3.1.tgz(r-4.4-emscripten)HIMA_2.3.1.tgz(r-4.3-emscripten)
HIMA.pdf |HIMA.html✨
HIMA/json (API)
NEWS

# Install 'HIMA' in R:

install.packages('HIMA', repos = c('https://yinanzheng.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/yinanzheng/hima/issues

Datasets:

BinaryOutcome - Binary Outcome Dataset for HIMA Demo
ContinuousOutcome - Continuous Outcome Dataset for HIMA Demo
MicrobiomeData - Compositional Mediator Dataset for HIMA Demo
QuantileData - Quantile Mediation Dataset for HIMA Demo
SurvivalData - Survival Outcome Dataset for HIMA Demo

On CRAN:

7.22 score 24 stars 23 scripts 544 downloads 3 mentions 7 exports 57 dependencies

Last updated 2 months agofrom:4bfd911733. Checks:8 OK. Indexed: yes.

Target	Result	Latest binary
Doc / Vignettes	OK	Mar 03 2025
R-4.5-win	OK	Mar 03 2025
R-4.5-mac	OK	Mar 03 2025
R-4.5-linux	OK	Mar 03 2025
R-4.4-win	OK	Mar 03 2025
R-4.4-mac	OK	Mar 03 2025
R-4.3-win	OK	Mar 03 2025
R-4.3-mac	OK	Mar 03 2025

Exports:hima hima_classic hima_dblasso hima_efficient hima_microbiome hima_quantile hima_survival

Dependencies:cli codetools colorspace conquer doParallel fansi farver fdrtool foreach ggplot2 glmnet glue gtable hdi HDMT hommel isoband iterators labeling lars lattice lifecycle linprog lpSolve magrittr MASS Matrix MatrixModels matrixStats mgcv munsell ncvreg nlme pillar pkgconfig plyr quantreg qvalue R6 RColorBrewer Rcpp RcppArmadillo RcppEigen reshape2 rlang scales scalreg shape SparseM stringi stringr survival tibble utf8 vctrs viridisLite withr

High-Dimensional Mediation Analysis

The HIMA Development Team

Rendered fromhima-vignette.Rmdusingknitr::rmarkdownon Mar 03 2025.

Last update: 2025-02-01
Started: 2025-01-23

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
High-Dimensional Mediation Analysis for 'Omic' Data	HIMA-package
Binary Outcome Dataset for HIMA Demo	BinaryOutcome
Continuous Outcome Dataset for HIMA Demo	ContinuousOutcome
High-dimensional Mediation Analysis	hima
Classic high-dimensional mediation analysis	hima_classic
High-dimensional mediation analysis with de-biased lasso penalty	hima_dblasso
Efficient high-dimensional mediation analysis	hima_efficient
High-dimensional mediation analysis for compositional microbiome data	hima_microbiome
High-dimensional quantile mediation analysis	hima_quantile
High-dimensional mediation analysis for survival data	hima_survival
Compositional Mediator Dataset for HIMA Demo	MicrobiomeData
Quantile Mediation Dataset for HIMA Demo	QuantileData
Survival Outcome Dataset for HIMA Demo	SurvivalData