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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "PathwayVote" in publications use:'
type: software
license: MIT
title: 'PathwayVote: Robust Pathway Enrichment for DNA Methylation Studies Using Ensemble
  Voting'
version: 0.1.3
doi: 10.32614/CRAN.package.PathwayVote
abstract: Performs pathway enrichment analysis using a voting-based framework that
  integrates CpG–gene regulatory information from expression quantitative trait methylation
  (eQTM) data. For a grid of top-ranked CpGs and filtering thresholds, gene sets are
  generated and refined using an entropy-based pruning strategy that balances information
  richness, stability, and probe bias correction. In particular, gene lists dominated
  by genes with disproportionately high numbers of CpG mappings are penalized to mitigate
  active probe bias—a common artifact in methylation data analysis. Enrichment results
  across parameter combinations are then aggregated using a voting scheme, prioritizing
  pathways that are consistently recovered under diverse settings and robust to parameter
  perturbations.
authors:
- family-names: Zheng
  given-names: Yinan
  email: y-zheng@northwestern.edu
  orcid: https://orcid.org/0000-0002-2006-7320
repository: https://yinanzheng.r-universe.dev
commit: 4b84a436e33e8a72104d7b7a2f41525b470609bc
date-released: '2026-01-19'
contact:
- family-names: Zheng
  given-names: Yinan
  email: y-zheng@northwestern.edu
  orcid: https://orcid.org/0000-0002-2006-7320